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 | Volume 9, Number 2 (9-2011) |  | |
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 | TG-60 dosimetry parameters calculation for the β-emitter 153Sm brachytherapy source using MCNP |  |
| | Author(s): F. Taghdiri, M. Sadeghi *, S.H. Hosseini , M. Athari | | * - Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Karaj, Iran , msadeghi@nrcam.org | | Study Type: Original Research | Subject: Radiation Biology | | | Article abstract: | |
Background: The formalism recommended by
Task Group 60 (TG-60) of the American Association of
Physicists in Medicine (AAPM) is applicable for β
sources. Radioactive biocompatible and biodegradable
153Sm glass seed without encapsulation is a β-
emitter with a short half life and delivers a high dose
rate to the tumor in the millimeter range. In this work
the dosimetry parameters of the seed for brachytherapy
were evaluated. Materials and Methods: Using
MCNP4C code data, the Dosimetric parameters of
AAPM TG-60 recommendations including the
reference dose rate, the radial dose function and the
anisotropy function were obtained. Two dimensional
dose distributions were also calculated. Results: The
dose rate at reference point was estimated to be
9.41 cGy.h-1.μCi-1 for 153Sm. 153Sm with its relatively
low energy beta component falls off the most rapidly
of the other beta emitters. The calculated data was
compared with that of several beta and photon
emitting seeds. Conclusion: The results showed the
advantage of the beta emitting 153Sm source in
comparison with the other beta emitting sources,
Because of its rapid dose fall-off of beta-ray and high
dose rate at the short distances of the seed. The
results would be helpful in development of the radioactive
implants using 153Sm seeds for the brachytherapy
treatment. Iran. J. Radiat. Res.,2011; 9(2): 103-108
| | | Keywords: Beta emitters, 153-Sm seed, dosimetry, TG- 60 protocol, MCNP4C code, | |
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